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rac-Bedaquiline diastereomer impurity

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rac-Bedaquiline diastereomer impurity, >98%

IUPAC Name : 1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol

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Chemical Properites
Mol. Formula :
C32H31BrN2O2
Mol. Weight :
555.52
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
1%TFA in MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Bedaquiline, which is an orally administered diarylquinoline. Bedaquiline serves as a bactericidal agent against mycobacteria by inhibiting proton-translocating ATP synthase.

References : Palmer D. B. et al.: J. Med. Chem., 58(7), 3036-3059, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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