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rac-Berotralstat

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SL-9308

rac-Berotralstat, >98%

IUPAC Name : 1-(3-(Aminomethyl)phenyl)-N-(5-((3-cyanophenyl)((cyclopropylmethyl)amino)methyl)-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C30H26F4N6O
Mol. Weight :
562.57
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : Berotralstat is an orally active plasma kallikrein inhibitor. It can reduce brain edema and is being studied for glioblastoma and hereditary angioedema.

References : Zuraw B. et al.: J. Allergy Clin. Immunol., S0091-6749(20), 31484-6, 2020; Richard E. K. et al.: Neuroglia 5(3), 223-233, 2024; Perego F. et al.: Expert Opin Biol Ther., 19(6), 517-526, 2019; Wan J. et al.: Blood Adv., 8(12), 3045-3057, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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