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rac-GDC-0834

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SI-5194

rac-GDC-0834, >98% (HPLC)

CAS No. : [1133432-46-8]

MDL No. : MFCD28716105

IUPAC Name : N-(3-(6-((4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenyl)amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide

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Chemical Properites
Mol. Formula :
C33H36N6O3S
Mol. Weight :
596.75
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : rac-GDC-0834 is the racemate form of GDC-0834, which is a potent and selective BTK inhibitor and has the potential for treatment of rheumatoid arthritis.

References : Liu L. et al.: J. Pharmacol Exp Ther., 338(1), 154-163, 2011; Liu L. et al.: Drug Metab Dispos., 39(10), 1840-1849, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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