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rac-Mavacamten-d5

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rac-Mavacamten-d5, >98%

Related CAS No. : 1642288-47-8] of the parent compound

Synonyms : rac-SAR-439152-d5; rac-MYK-461-d5

IUPAC Name : 3-Isopropyl-6-((1-(phenyl-d5)ethyl)amino)pyrimidine-2,4(1H,3H)-dione

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C15H14D5N3O2
Mol. Weight :
278.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Mavacamten, is a first-in-class cardiac myosin inhibitor used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM).

References : Kawas R. F. et al.: J. Biol. Chem., 292(40), 16571-16577, 2017; Stern J. A. et al.: PLoS One 11(12), e0168407, 2016; Green E. M. et al.: Science 351(6273), 617-21, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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