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rac-Pyrotinib

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SI-5269

rac-Pyrotinib, >98% (HPLC)

CAS No. : [1246089-97-3]

Synonyms : rac-SHR-1258

IUPAC Name : (E)-4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(4-(1-methylpyrrolidin-2-yl)-2-oxobut-3-en-1-yl)quinoline-3-carbonitrile

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Chemical Properites
Mol. Formula :
C33H32ClN5O3
Mol. Weight :
582.10
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : rac-Pyrotinib is the racemate of Pyrotinib, which is a potent and selective EGFR/HER2 dual inhibitor. Developed for the treatment of HER2-positive advanced solid tumours.

References : Li X. et al.: Eur J Pharm Sci., pii: S0928-0987(17), 30043, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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