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rac-Ramelteon

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SL-11505

rac-Ramelteon, >98%

CAS No. : [196597-17-8]

Synonyms : rac-TAK-375

IUPAC Name : N-(2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl)propionamide

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Chemical Properites
Mol. Formula :
C16H21NO2
Mol. Weight :
259.35
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a racemic form of Ramelteon, which is a potent, highly selective, and orally active agonist of MT1/MT2. It has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation.

References : Kato K. et al.: Neuropharmacology 48(2), 301-310, 2005; Mayer G. et al.: Sleep, 32(3), 351-360, 2009; Hirai K. et al.: J. Biol Rhythms, 20(1), 27-37, 2005; Miyamoto M. et al.: Sleep, 27(7), 1319-1325, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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