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rac-Tezacaftor

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SL-11714

rac-Tezacaftor, >98%

CAS No. : [1226709-85-8]

Synonyms : rac-VX-661

IUPAC Name : 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C26H27F3N2O6
Mol. Weight :
520.51
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a racemic form of Tezacaftor, which is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Tezacaftor is used for the treatment of cystic fibrosis (CF).

References : Zemanick T. E. et al.: Am. J. Respir. Crit. Care. Med., 203(12), 1522-1532, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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