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Ralaniten

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SI-7336

Ralaniten, >98% (HPLC)

CAS No. : [1203490-23-6]

Synonyms : EPI-002

IUPAC Name : (R)-3-(4-(2-(4-((S)-3-Chloro-2-hydroxypropoxy)phenyl)propan-2-yl)phenoxy)propane-1,2-diol

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Chemical Properites
Mol. Formula :
C21H27ClO5
Mol. Weight :
394.89
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ralaniten selectively targets the intrinsically disordered N‑terminal domain of the androgen receptor, blocking AR‑regulated transcription with an IC50 of 7.4 µM. Its unique mechanism supports its use in probing AR signaling and therapeutic strategies in CRPC models.

References : Myung J. K. et. al.: J. Clin Invest, 123(7), 2948-60, 2013; Yang Y. C. et. al.: Clin Cancer Res., 22(17), 4466-77, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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