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Ralaniten triacetate

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SI-7337

Ralaniten triacetate, >98% (HPLC)

CAS No. : [1637573-04-6]

Synonyms : EPI-506

IUPAC Name : (S)-3-(4-(2-(4-((S)-2-Acetoxy-3-chloropropoxy)phenyl)propan-2-yl)phenoxy)propane-1,2-diyl diacetate

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Chemical Properites
Mol. Formula :
C27H33ClO8
Mol. Weight :
521
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ralaniten triacetate is an orally active pro‑agent of Ralaniten that selectively targets the intrinsically disordered AR N‑terminal domain. It effectively inhibits signaling driven by full‑length AR and resistance‑related splice variants, including AR‑V7, making it valuable for studying therapeutic strategies in castration‑resistant prostate cancer.

References : Obst J. K. et al.: ACS Pharmacol Transl Sci, 2(6), 453-467, 2019; Nguyen K. C. et al.: Journal of Clinical Oncology, 35, 5032-5032, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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