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Ralometostat

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SI-8106

Ralometostat, >98% (HPLC)

CAS No. : [2760481-53-4]

Synonyms : TNG-908

IUPAC Name : N-(6-Amino-5-methylpyridin-3-yl)-2-((2R,5S)-2-(benzo[d]thiazol-5-yl)-5-methylpiperidin-1-yl)-2-oxoacetamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H23N5O2S
Mol. Weight :
409.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ralometostat is an MTAP‑synergistic PRMT5 inhibitor with oral activity and confirmed blood–brain‑barrier penetration. Its MTAP‑dependent selectivity supports its use in mechanistic and therapeutic research across MTAP‑deficient cancer models.

References : Briggs K. et al.: E. J. Cancer, 174(1), S84, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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