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Raloxifene-d8 dimer

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SL-3836

Raloxifene-d8 dimer, >98% (CP)

Isotopic Purity : 98 atom % D

IUPAC Name : [6,6'-Dihydroxy-2,2'-bis(4-hydroxyphenyl)[7,7'-bibenzo[b]thiophene]-3,3'-diyl]bis[[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone-d8

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Chemical Properites
Mol. Formula :
C56H44D8N2O8S2
Mol. Weight :
953.20
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Raloxifene-d8 dimer is a deuterium labelled version an analog of Raloxifene, which is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.

References : Obach R. S. et al.: Drug Metab Dispos., 32(1), 89-97, 2004; Yang N. N. et al.: Endocrinology., 137(5), 2075-2084, 1996; Black L. J. et al.: J. Clin Invest., 93(1), 63-69, 1994; Evans G. et al.: Endocrinology, 134(5), 2283-2288, 1994; Sato M. et al.: FASEB J, 10(8), 905-912, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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