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Raloxifene dimer

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Raloxifene dimer, >98%

CAS No. : [618902-12-8]

IUPAC Name : 6,6'-Dihydroxy-2,2'-bis(4-hydroxyphenyl)[7,7'-bibenzo[b]thiophene]-3,3'-diyl]bis[[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone

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Chemical Properites
Mol. Formula :
C56H52N2O8S2
Mol. Weight :
945.15
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Raloxifene dimer is an impurity of Raloxifene, which is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.

References : Obach R. S. et al.: Drug Metab Dispos., 32(1), 89-97, 2004; Yang N. N. et al.: Endocrinology., 137(5), 2075-2084, 1996; Black L. J. et al.: J. Clin Invest., 93(1), 63-69, 1994; Evans G. et al.: Endocrinology, 134(5), 2283-2288, 1994; Sato M. et al.: FASEB J, 10(8), 905-912, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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