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Raltegravir

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SI-5884

Raltegravir, >98% (HPLC)

CAS No. : [518048-05-0]

MDL No. : MFCD10698872

Synonyms : MK-0518

IUPAC Name : N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide

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Chemical Properites
Mol. Formula :
C20H21FN6O5
Mol. Weight :
444.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Raltegravir is a potent integrase (IN) inhibitor, can be used to treat HIV infection.

References : Hare S. et al.: Proc Natl Acad Sci U S A 107(46), 20057-62, 2010;
Xu P. et al.: J. Neuroimmune Pharmacol., 12(4), 682-692, 2017; Hicks C. et al.: Clin Infect Dis., 48(7), 931-9, 2009; Moss D. M. et al.: Antimicrob Agents Chemother., 56(6), 3020-6, 2012; Hare S. et al.: Mol Pharmacol., 80(4), 565-72, 2011; Lewis M.G. et al.: Retrovirology. 7, 21, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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