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Ramelteon-d3

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SL-11502

Ramelteon-d3, >98%

CAS No. : [1432057-38-9]

Synonyms : TAK-375-d3

IUPAC Name : (S)-N-(2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl)propanamide-d3

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Chemical Properites
Mol. Formula :
C16H18D3NO2
Mol. Weight :
262.37
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Ramelteon-d3 is a deuterium-labelled version of Ramelteon. This can be used as an analytical labelled reference standard. Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2. It has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation.

References : Kato K. et al.: Neuropharmacology 48(2), 301-310, 2005; Mayer G. et al.: Sleep, 32(3), 351-360, 2009; Hirai K. et al.: J. Biol Rhythms, 20(1), 27-37, 2005; Miyamoto M. et al.: Sleep, 27(7), 1319-1325, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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