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RB-64

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SI-7635

RB-64, >98% (HPLC)

CAS No. : [1174223-49-4]

Synonyms : 22-Thiocyanatosalvinorin A

IUPAC Name : Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2-thiocyanatoacetoxy)dodecahydro-2H-benzo[f]isochromene-7-carboxylate

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Chemical Properites
Mol. Formula :
C24H27NO8S
Mol. Weight :
489.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : RB‑64 selectively activates the κ‑opioid receptor with remarkable potency (EC50 = 0.077 nM). Its pharmacological profile supports its use in studying KOR‑dependent pathways and biased signaling mechanisms.

References : Yan F. et al.: Biochemistry, 48(29), 6898-908, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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