Rebastinib

SI-8008

Rebastinib, >98% (HPLC)

CAS No. : [1020172-07-9]

Synonyms : DCC‑2036

IUPAC Name : 4-(4-(3-(3-(Tert-butyl)-1-(quinolin-6-yl)-1H-pyrazol-5-yl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Rebastinib is a potent, orally active Bcr‑Abl inhibitor that operates through a non‑ATP‑competitive mechanism, inhibiting Abl1^WT and Abl1^T315I at 0.8 nM and 4 nM, respectively. It also targets SRC, KDR, FLT3, and Tie‑2, while exhibiting low activity toward c‑Kit, reflecting a focused yet multi‑kinase profile.

References : Chan W. W. et al.: Cancer Cell, 19(4), 556-568, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.