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SI-5477

Redafamdastat, >98% (HPLC)

CAS No. : [1020315-31-4]

MDL No. : MFCD18782721

Synonyms : PF-04457845

IUPAC Name : N-(Pyridazin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzylidene)piperidine-1-carboxamide

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Chemical Properites
Mol. Formula :
C23H20F3N5O2
Mol. Weight :
455.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-04457845 is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.

References : Johnson D. S. et al.: ACS Med Chem Lett., 2(2), 91-96, 2011; Ahn K. et al.: J. Pharmacol Exp Ther., 338(1), 114-24, 2011; Buntyn R. W. et al.: Int. J. Toxicol., 36(5), 395-402, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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