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Refametinib

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SI-5598

Refametinib, >98% (HPLC)

CAS No. : [923032-37-5]

MDL No. : MFCD18633256

Synonyms : BAY 869766; RDEA119

IUPAC Name : (S)-N-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide

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Chemical Properites
Mol. Formula :
C19H20F3IN2O5S
Mol. Weight :
572.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Refametinib is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with potential antineoplastic activity.

References : Iverson C. et al.: Cancer Res., 69(17), 6839-47, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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