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Regorafenib (Pyridine)-N-Oxide

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SL-378

Regorafenib (Pyridine)-N-Oxide, >98%

CAS No. : [835621-11-9]

MDL No. : MFCD28343981

Synonyms : BAY 75-7495

IUPAC Name : 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-oxide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
10MG75.00
Back Order  Estimated to ship on 04 October 2026
25MG145.00
Back Order  Estimated to ship on 04 October 2026
50MG245.00
Back Order  Estimated to ship on 04 October 2026
100MG355.00
Back Order  Estimated to ship on 04 October 2026
250MG755.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H15ClF4N4O4
Mol. Weight :
498.81
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Regorafenib-N-oxide is a major metabolite M2 of Regorafenib (BAY 75-7495), formed during the metabolism of Regorafenib by CYP3A4 and found to be pharmacologically equally active as parent drug.

References : Sunakawa Y.et.al.: Invest. New Drugs, 32, 104, 2014.

Storage : Keep container tightly closed under nitrogen or argon and store at -20oC for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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