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Relugolix impurity 23

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Relugolix impurity 23, >98%

CAS No. : [1589503-93-4]

Synonyms : Relugolix amine impurity

IUPAC Name : 6-(4-Aminophenyl)-1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

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Chemical Properites
Mol. Formula :
C27H24F2N6O3S
Mol. Weight :
550.58
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Relugolix, which is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. It is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer.

References : Miwa K. et al.: J. Med. Chem., 54(14), 4998-5012, 2011; Nakata D. et al.: Eur J. Pharmacol., 723, 167-174, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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