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Remdesivir n-butyl impurity

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Remdesivir n-butyl impurity, >98%

IUPAC Name : Butyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate

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Chemical Properites
Mol. Formula :
C25H31N6O8P
Mol. Weight :
574.53
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Remdesivir, which is a monophosphoramidate prodrug of an adenosine analog, and an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.

References : Warren T. K. et al.: Nature 531(7594), 381-385, 2016; Agostini M. L. et al.: mBio 9(2), 6, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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