Remdesivir tri-(O)-benzyl nitrile impurity

SL-11536

Remdesivir tri-(O)-benzyl nitrile impurity, >98%

CAS No. : [1355357-49-1]

IUPAC Name : (2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-carbonitrile

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Applications : This is an impurity of Remdesivir, which is a monophosphoramidate prodrug of an adenosine analog, and an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.

References : Warren T. K. et al.: Nature 531(7594), 381-385, 2016; Agostini M. L. et al.: mBio 9(2), 6, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.