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Remibrutinib

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SI-6079

Remibrutinib, >98% (HPLC)

CAS No. : [1787294-07-8]

Synonyms : LOU-064

IUPAC Name : N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C27H27F2N5O3
Mol. Weight :
507.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Remibrutinib potently inhibits BTK (IC50 = 1 nM) and shows strong target engagement in whole blood (IC50 = 0.023 µM). Its pharmacological profile supports its development for chronic urticaria and other immune‑mediated disorders.

References : Kolkhir P. et al.: Ann Allergy Asthma Immunol., 124(1), 2-12, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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