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Remogliflozin

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SL-9832

Remogliflozin, >98%

CAS No. : [329045-45-6]

Synonyms : Remogliflozin A

IUPAC Name : (2S,3R,4R,5S,6R)-2-(Hydroxymethyl)-6-((4-(4-isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol

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Chemical Properites
Mol. Formula :
C23H34N2O7
Mol. Weight :
450.53
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with Kis of 12.4 and 26 nM for human and rat SGLT2, respectively. Remogliflozin is used to treat type 2 diabetes mellitus.

References : Fujimori Y. et al.: J. Pharmacol Exp. Ther., 327(1), 268-76, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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