Repotrectinib

SI-5569

Repotrectinib, >98% (HPLC)

CAS No. : [1802220-02-5]

Synonyms : TPX-0005

IUPAC Name : (13E,14E,3R,6S)-45-Fluoro-3,6-dimethyl-5-oxa-2,8-diaza-1(5,3)-pyrazolo[1,5-a]pyrimidina-4(1,2)-benzenacyclononaphan-9-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026
5G	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Repotrectinib is a potent ROS1 (IC50=0.07 nM) and TRK (IC50=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK (IC50=1.01 nM). Repotrectinib has anticancer activity.

References : Karachaliou N. et al.: EBioMedicine 29, 112-127, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.