Resigratinib

SI-7547

Resigratinib, >98% (HPLC)

CAS No. : [2750709-91-0]

Synonyms : KIN-3248

IUPAC Name : 1-((3S,5R)-1-Acryloyl-5-(methoxymethyl)pyrrolidin-3-yl)-3-((1-cyclopropyl-4,6-difluoro-1H-benzo[d]imidazol-5-yl)ethynyl)-5-(methylamino)-1H-pyrazole-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Resigratinib covalently targets FGFR1–4 through binding to Cys492, inhibiting both wild‑type and resistant FGFR mutants such as FGFR2 V565F and FGFR3 V555M. It blocks downstream FGFR signaling, reduces proliferation, and induces apoptosis in tumor cells, making it a valuable tool for research on FGFR2/3‑dependent cancers.

References : Tyhonas J. S. et al.: J. Med. Chem., 67(3), 1734-1746, 2024; Balasooriya E. R. et al.: Clin. Cancer Res., 30(10), 2181-2192, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.