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Resminostat hydrochloride

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SL-1630

Resminostat hydrochloride, >98%

CAS No. : [1187075-34-8]

MDL No. : MFCD26142920

Synonyms : RAS2410 hydrochloride; 4SC-201 hydrochloride

IUPAC Name : (E)-3-[1-(4-Dimethylaminomethyl-benzenesulfonyl)-1H-pyrrol-3-yl]N-hydroxy-acrylamide hydrochloride

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Chemical Properites
Mol. Formula :
C16H19N3O4S . HCl
Mol. Weight :
385.87
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM.

References : Mandl-Weber S. et al.:Br J Haematol., 149(4), 518-228, 2010; Enzenhofer E. et al.: Head Neck. 39(5), 900-907, 2017; Peng X. et al.: Biochem Biophys Res Commun., 477(4), 556-562,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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