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Retigabine

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SI-4291

Retigabine, >98% (HPLC)

CAS No. : [150812-12-7]

MDL No. : MFCD04307735

IUPAC Name : Ethyl (2-amino-4-((4-fluorobenzyl)amino)phenyl)carbamate

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Chemical Properites
Mol. Formula :
C16H18FN3O2
Mol. Weight :
303.33
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Retigabine is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.

References : Ding H. X. et al.: Bioorg. Med. Chem. 21(11), 2795-2825, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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