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Revefenacin

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SI-5112

Revefenacin, >98% (HPLC)

CAS No. : [864750-70-9]

MDL No. : MFCD28386316

Synonyms : GSK-1160724; TD-4208

IUPAC Name : 1-(2-(4-((4-Carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate

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Chemical Properites
Mol. Formula :
C35H43N5O4
Mol. Weight :
597.76
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Revefenacin is a potent mAChR antagonist; has a high affinity on M3 receptor with a Ki of 0.18 nM. Revefenacin is used to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

References : Steinfeld T. et al.: Am. J. Respir Crit Care Med 179, A4553, 2009; Pulido-Rios M. T. et al.: J. Pharmacol Exp Ther., 346(2), 241-50, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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