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Reversine

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SI-4105

Reversine, >98% (HPLC)

CAS No. : [656820-32-5]

MDL No. : MFCD09953189

IUPAC Name : N6-Cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine

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Chemical Properites
Mol. Formula :
C21H27N7O
Mol. Weight :
393.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC50s of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively.

References : Liu Y. et al.: J. Med. Chem., 58(8), 3366-3392, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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