RGB-286638 free base

SI-7809

RGB-286638 free base, >98% (HPLC)

CAS No. : [784210-88-4]

IUPAC Name : 1-(3-(4-((4-(2-Methoxyethyl)piperazin-1-yl)methyl)phenyl)-4-oxo-1,4-dihydroindeno[1,2-c]pyrazol-5-yl)-3-morpholinourea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : RGB‑286638 potently inhibits multiple CDKs—including CDK9, CDK1, CDK2, CDK4, CDK3, and CDK5—with IC₅₀ values ranging from 1–5 nM. It additionally targets GSK‑3β (3 nM), TAK1 (5 nM), JAK2 (50 nM), and MEK1 (54 nM). This broad kinase‑inhibition profile makes RGB‑286638 a valuable tool for dissecting CDK‑regulated cell‑cycle progression and diverse signaling pathways.

References : Cirstea D. et al.: Leukemia, 27(12), 2366-75, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.