RGH-122

SI-7478

RGH-122, >98% (HPLC)

CAS No. : [2355304-05-9]

IUPAC Name : 8-Chloro-1-((1r,4S)-4-(pyridin-2-yloxy)cyclohexyl)-4H,6H-spiro[benzo[f][1,2,4]triazolo[4,3-a]azepine-5,2'-[1,3]dioxolane]

Price And Availability
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25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : RGH‑122 potently and selectively antagonizes the hV1a receptor (K_i= 0.3 nM; IC₅₀ = 0.9 nM) and shows good microsomal stability, with CLint values of 13/28/25 µL/min/mg. Its potency and metabolic profile make it a valuable tool for investigating vasopressin V1a‑dependent pathways.

References : Baska F. et al.: J. Med. Chem., 67(1), 643-673, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.