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Ricolinostat

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SL-1632

Ricolinostat, >98%

CAS No. : [1316214-52-4]

MDL No. : MFCD22666356

Synonyms : Rocilinostat; ACY-1215

IUPAC Name : 2-(Diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide

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Chemical Properites
Mol. Formula :
C24H27N5O3
Mol. Weight :
433.50
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ricolinostat is a potent and selective HDAC6 inhibitor, with an enzymatic IC50 value of 5 nM. ACY-1215 also inhibits HDAC1, HDAC2, and HDAC3 with IC50 of 58, 48, and 51 nM, respectively.

References : Santo L. et al.: Blood 119(11), 2579-2589, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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