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Rimonabant

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SI-7686

Rimonabant, >98% (HPLC)

CAS No. : [168273-06-1]

Synonyms : SR-141716A

IUPAC Name : 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide

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Chemical Properites
Mol. Formula :
C22H21Cl3N4O
Mol. Weight :
463.79
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Rimonabant selectively antagonizes central CB1 receptors with high potency (Ki = 1.8 nM) and demonstrates strong brain penetration. Beyond its cannabinoid‑modulatory effects, it also targets the mycobacterial transporter MMPL3.

References : Seely K. A. et al.: Neuropharmacology, 63(5), 9, 2012; Leite C. E. et al.: Pharmacol. Rep., 61, 217-224 , 2009; Zhang B. et al.: Cell, 176(3), 636-648.e13, 2019; Erdozain. A. M. et al.: Biochemical Pharmacology, 83(2), 260-268, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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