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Rimonabant hydrochloride

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SI-7688

Rimonabant hydrochloride, >98% (HPLC)

CAS No. : [158681-13-1]

Synonyms : SR-141716A hydrochloride

IUPAC Name : 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride

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Chemical Properites
Mol. Formula :
C22H21Cl3N4O • HCl
Mol. Weight :
500.25
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Rimonabant hydrochloride selectively antagonizes CB1 receptors with sub‑nanomolar affinity (Ki = 1.8 nM) and demonstrates strong central penetration. It also targets the mycobacterial transporter MMPL3, expanding its pharmacological profile.

References : Seely K. A. et al.: Neuropharmacology, 63(5), 905-15, 2012; Zhang B. et al.: Cell, 176(3),636-648, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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