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Riociguat impurity 9

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SL-3942

Riociguat impurity 9, >98%

Synonyms : 2-Desfluoro-4-fluoro-riociguat; p-Riociguat (p-isomer)

IUPAC Name : Methyl (4,6-diamino-2-(1-(4-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate

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Chemical Properites
Mol. Formula :
C20H19FN8O2
Mol. Weight :
422.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Riociguat (Riociguat impurity 9), which is an oral stimulator of soluble guanylate cyclase (sGC), used in the treatment of pulmonary hypertension.

References : Oncogene 38(22), 4397-4411, 2019; Endocr Relat Cancer 26(2), 251-264, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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