RIP1 kinase inhibitor 5

SI-7489

RIP1 kinase inhibitor 5, >98% (HPLC)

CAS No. : [2428422-17-5]

IUPAC Name : N-(3,5-Difluorobenzyl)-N-hydroxy-2,2-dimethylbutanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This potently inhibits RIP1, a checkpoint kinase involved in tumor‑immune regulation. It shows mechanistic similarity to SIR1‑365, which blocks necrosis and ferroptosis. Together, these properties make it useful for studying RIP1‑mediated cell‑death pathways in cancer biology.

References : Chavez-Tapia N. et al.: J. Intensive Med., 5(1):70-78, 2024; Alba G. A. et al. E. ClinicalMedicine, 39, 101066, 2021; Ren Y. et al. J. Med. Chem., 60(3), 972-986, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.