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Ripasudil

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SI-3551

Ripasudil, >98% (HPLC)

CAS No. : [223645-67-8]

Synonyms : K-115

IUPAC Name : (S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline

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Chemical Properites
Mol. Formula :
C15H18FN3O2S
Mol. Weight :
323.39
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Ripasudil is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.

References : Flick C. A. et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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