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Rislenemdaz

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SI-7623

Rislenemdaz, >98% (HPLC)

CAS No. : [808732-98-1]

Synonyms : MK-0657; CERC-301

IUPAC Name : 4-Methylbenzyl (3S,4R)-3-fluoro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate

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Chemical Properites
Mol. Formula :
C19H23FN4O2
Mol. Weight :
358.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Rislenemdaz selectively targets GluN2B‑subunit NMDA receptors and demonstrates strong potency (Ki= 8.1 nM; IC50 = 3.6 nM). Its oral bioavailability and subtype selectivity make it a valuable tool for probing NMDA‑dependent excitotoxic and neurobehavioral pathways.

References : Garner R. et al.: Pharmacol. Res. Perspect., 3(6), e00198, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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