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RMC-0331

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SI-7492

RMC-0331, >98% (HPLC)

CAS No. : [2488788-52-7]

Synonyms : RM-023

IUPAC Name : (R)-(4-((1-(3-Amino-5-(trifluoromethyl)phenyl)ethyl)amino)-2-chloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)(4-methoxytetrahydro-2H-pyran-4-yl)methanone

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Chemical Properites
Mol. Formula :
C22H25ClF3N5O3
Mol. Weight :
499.92
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : RMC‑0331 selectively inhibits SOS1 and blocks RAS activation by preventing formation of the RAS–SOS1 complex. With strong oral bioavailability and in vivo utility, it serves as a valuable tool for studying SOS1‑regulated RAS signaling pathways.

References : Andreas Buckl. et al.: Cancer Res., 81(13), 1273, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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