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RMC-4550

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SI-7054

RMC-4550, >98% (HPLC)

CAS No. : [2172651-73-7]

IUPAC Name : (3-((3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-6-(2,3-dichlorophenyl)-5-methylpyrazin-2-yl)methanol

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Chemical Properites
Mol. Formula :
C21H26Cl2N4O2
Mol. Weight :
437.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : RMC‑4550 functions as a selective allosteric SHP2 inhibitor with exceptional potency (IC50 = 0.583 nM), making it a valuable tool for probing SHP2‑dependent signaling pathways.

References : Nichols R. J. et al.: Nat. Cell Biol., 20(9), 1064-1073, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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