RMS-07

SI-6933

RMS-07, >98% (HPLC)

CAS No. : [2645409-78-3]

IUPAC Name : 2-((2-Acrylamido-4-(4-methylpiperazin-1-yl)phenyl)amino)-N-(2,6-diethylphenyl)-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : RMS‑07 covalently inhibits the mitotic checkpoint kinase Mps1/TTK with strong potency (apparent IC₅₀ = 13.1 nM). Its mechanism involves engagement of a poorly conserved hinge‑region cysteine, providing a structural basis for selectivity.

References : Ricardo A. M. Serafim et al.: J. Med. Chem., 65(4), 3173-3192, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.