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SI-7729
RO-281675, >98% (HPLC)
CAS No. : [300353-13-3]
IUPAC Name : (R)-3-Cyclopentyl-2-(4-(methylsulfonyl)phenyl)-N-(thiazol-2-yl)propanamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C18H22N2O3S2 | Mol. Weight : 378.51 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : RO‑281675 activates glucokinase allosterically with high potency (EC50 = 54 nM) and is widely used to probe GK‑dependent pathways and glucose homeostasis in type 2 diabetes research.
References : Haynes E. N. et al.: J. Med. Chem., 53(9), 3618-25, 2010; Grimsby J. et al.: Science, 301(5631), 370-3, 2003.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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