RO-907501

SI-6713

RO-907501, >98% (HPLC)

CAS No. : [293762-45-5]

IUPAC Name : 2'-(4-Aminophenyl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-5-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : RO 907501 inhibits Aβ42 fibrillization and reduces Aβ42‑induced toxicity. It blocks ATM activation and DNA repair, enhances TLR3/RLR‑mediated IFN‑β responses, and functions as a TPR‑dependent PP5 inhibitor. In cancer models, Ro 90‑7501 produces strong radiosensitizing effects, particularly in cervical cancer cells.

References : Bohrmann B. et al.: J. Struct. Biol., 130(2-3), 232-46, 2000; Tamari K. et al.: Anticancer Res., 39(9), 4805-4810, 2019; Guo F. et al.: PLoS One., 7(10), e42583, 2012; Hong T. J. et al.: Biochem. Biophys. Res. Commun., 482(2), 215-220, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.