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Roblitinib

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SI-7068

Roblitinib, >98% (HPLC)

CAS No. : [1708971-55-4]

Synonyms : FGF-401

IUPAC Name : N-(5-Cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide

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Chemical Properites
Mol. Formula :
C25H30N8O4
Mol. Weight :
506.57
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Roblitinib selectively inhibits FGFR4 with low‑nanomolar potency (IC50 = 1.9 nM) and displays robust antitumor effects in FGFR4‑dependent systems.

References : Robin A. Fairhurst et al.: J. Med. Chem., 63(21), 12542-12573, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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