Rodatristat

SI-6267

Rodatristat, >98% (HPLC)

CAS No. : [1673568-73-4]

Synonyms : KAR-5417

IUPAC Name : (S)-8-(2-Amino-6-((R)-1-(5-chloro-[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Rodatristat inhibits TPH1 and TPH2 with nanomolar potency (IC₅₀ = 33 nM and 7 nM) and significantly lowers intestinal serotonin levels in mice, making it a valuable tool for probing peripheral 5‑HT biology.

References : Goldberg D. R. et al.: Bioorg. Med. Chem. Lett., 27(3), 413-419, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.