Roflumilast

SI-1799

Roflumilast, 98% (HPLC)

CAS No. : [162401-32-3]

MDL No. : MFCD00938270

IUPAC Name : 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4- (difluoromethoxy)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	65.00		In Stock	Estimated to ship on 20 September 2026
10MG	75.00		In Stock	Estimated to ship on 20 September 2026
25MG	115.00		In Stock	Estimated to ship on 20 September 2026
50MG	155.00		In Stock	Estimated to ship on 20 September 2026
100MG	255.00		In Stock	Estimated to ship on 20 September 2026
250MG	455.00		In Stock	Estimated to ship on 20 September 2026
500MG	855.00		In Stock	Estimated to ship on 20 September 2026

Applications : Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.

References : Hatzelmann A. et al.: Pulm Pharmacol Ther., 23(4), 235-256, 2010; Rabe K. F. Br. J. Pharmacol., 163(1), 53-67, 2011; Hatzelmann A. et al.: J. Pharmacol Exp Ther., 297(1), 267-279, 2001; Richmond B. W. et al.: Nat. Commun. 7, 11240, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.