Roflumilast-d4

SL-6462

Roflumilast-d₄, >98% (HPLC)

Isotopic Purity : 99 atom % D

CAS No. : [1398065-69-4]

IUPAC Name : 3-((Cyclopropyl-d₄)methoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : Roflumilast-d₄ is a deuterium labelled version of Roflumilast, which is a selective phosphodiesterase-4 (PDE-4) inhibitor, used in the treatment of severe chronic obstructive pulmonary disease (COPD).

References : Hatzelmann A. et al.: Pulm Pharmacol Ther., 23(4), 235-256, 2010; Rabe K. F. Br. J. Pharmacol., 163(1), 53-67, 2011; Hatzelmann A. et al.: J. Pharmacol Exp Ther., 297(1), 267-279, 2001; Richmond B. W. et al.: Nat. Commun. 7, 11240, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.