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RORgammat inverse agonist 23

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SI-6848

RORγt inverse agonist 23, >98% (HPLC)

CAS No. : [2230779-18-5]

IUPAC Name : N-Cyclobutyl-N-(4-ethylphenyl)-4-hydroxy-2-(tetrahydro-2H-pyran-4-yl)chromane-6-sulfonamide

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Chemical Properites
Mol. Formula :
C26H33NO5S
Mol. Weight :
471.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an orally active, selective inverse agonist of RORγt with strong potency, making it a valuable tool for probing RORγt‑regulated transcription and Th17‑driven immune responses.

References : Chen L. et al.: J. Med. Chem. 64(21),16106-16131, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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