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CAS No. : [186692-46-6]
Synonyms : Seliciclib; CYC-202
IUPAC Name : (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C19H26N6O | Mol. Weight : 354.46 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Roscovitine selectively inhibits CDK5, Cdc2, and CDK2 with IC50 values of 0.2–0.7 µM and is both orally bioavailable and BBB‑permeable. It is commonly used to study CDK‑dependent signaling in proliferative and neurological models.
References : Meijer L. et al.: Eur J. Biochem., 243(1-2), 527-36, 1997; Tirado O. M. et al.: Cancer Res, 65(20), 9320-9327, 2005; Mgbonyebi O. P. et al.: Cancer Res., 59(8), 1903-10, 1999.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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